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Visual Optics and Biophotonics Lab - CSIC - Madrid

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Capabilities

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  Lab Technological Offer

 Development of optical instruments for in vivo assessment of the eye

Experience in designing and building optical imaging instruments, including double-pass technique, ocular aberrometry, ocular biometry (Purkinje, Scheimpflug imaging, OCT), adaptive optics, high resolution retinal imaging, retinal reflectometry and microscopy. Custom-development of optics, electronics & mechanical.

 Measurement of optical quality of the eye

Measurements of monochromatic and chromatic aberrations. Assessment of optical quality in normal, pathological (i.e. keratoconus), and treated eyes (refractive surgery, contact lenses, intrastromal ring segment, IOLs).

 Quantitative ocular biometry and geometry

Measurement of anterior and posterior corneal and lens topography, 3-D biometry, lens misalignment, GRIN (in vitro)

 Customized optical modeling

Development of custom pseudophakic eye models, based on individual biometry, and ray-tracing based optical predictions (and contributions of different factors) from these models.

 Intraocular Lens Design

We have developed analytical tools for customized intraocular lens design. In addition, we have experience in assessing optical properties in vivo in eyes with intraocular lens implanted, as well as measuring optical performance of IOLs in custom-designed water cell models, and customize computer modelling of pseudophakic eyes.

  Experimental model eyes

Water-cell model eyes for instrument validation and lens testing. Experience in measurements on a wide range of animal models in vivo and ex vivo.

 Corneal biomechanical testing

Custom develop eye inflation models; Scheimplug-based and OCT-based air puff corneal deformation testing. In normal and treated (cross-linking) eyes.

 Mechanical modeling

Finite-element modeling for retrieval of corneal biomechanical properties (elastic and viscoelastic parameters), as well as for intraocular lens assessment and design

 Psychophysical testing of visual perception and visual performance

Visual simulation through manipulated optics (aberration correction, combinations of aberrations, presbyopic corrections) in Adaptive Optics custom-development instrument. Psyschophysical routines for measurement of visual function, visual perception and neural adaptation