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Technological Offer

 Technological Offer


The technologies described below, are ready to be transferred to the industry, with the support of our group in most cases, and through licensing agreements with the Technology Transfer Office of our institution (CSIC)

 

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 Method of preventing the induction of aberrations in laser refractive surgery systems

 
CSIC offers a free, non exclusive license to laser manufacturers for some of the claims, in order to help innitiatives to improve refractive surgery outcomes. 
 
CSIC TIC006- Method of preventing the induction of aberrations in laser refractive surgery systems
A Spanish research institute has patented a method for preventing the induction of aberrations in laser refractive surgery systems (and therefore improving visual quality in patients) and for lens production. The invention relates to a systematic method that can be used with any system and ablation profile in order to obtain a profile correction factor. The research institute is looking for industrial partners interested in its exploitation
Specification sheet:
DESCRIPTION

Standard laser refractive surgery systems correct low-order refractive errors (myopia, hyperopia, astigmatism) successfully. However it has been shown that they induce spherical aberration and, by extension, other high-order aberrations, which results in degradation of visual quality. This increase in spherical aberration is due to the shape of the cornea, and not inherent to the theoretical ablation profile. As a result the problem is, in principle, common to any laser system.

This procedure consists of a systematic method that can be used with any system and ablation profile in order to obtain a profile correction factor. The method is based on the ablation of flat and spherical surfaces of plastic material, and takes into account the differences in ablation rates and thresholds between plastics and corneal tissue. This correction factor, which is specific to each system, can be applied to prevent the induction of spherical aberration, resulting in an improvement of optical and visual quality in patients following surgery, compared to surgery performed with standard systems. In addition, this method can be used to improve the manufacturing of lenses with controlled high-order aberration.

INNOVATIVE ASPECTS

The procedure represents a systematic calibration for any laser system (for refractive surgery in particular, and lens fabrication in general) to correct for laser ablation efficiency changes across a surface, and therefore to avoid the induction of high-order spherical aberrations

COMPETITIVE ADVANTAGES

Standard laser refractive surgery systems correct successfully low-order refractive errors but induce spherical aberrations (and by extension other high-order aberration) that result in degradation of visual quality. This increase of spherical aberration is primarily due to the geometry of the cornea, and not inherent to the theoretical ablation profile. For this reason the problem is common to any laser system. This invention proposes a systematic procedure to obtain a correction factor for the ablation profile, which can be applied to any laser system and ablation profile.

The application of this correction factor, specific to each system, will avoid the induction of spherical aberration, and therefore will provide an improvement of the optical and visual quality of patients after surgery, in comparison with conventional surgery. In addition, this procedure can be extended to the improvement of the manufacture of lenses with controlled high-order aberration by laser photo-sculpture

KEYWORDS

Laser Technology;Optics;Medicine, Human Health;Surgery;Other transportation;Optical Technology related to measurements

PATENT

Patents applications filed: PCT, EP, ES, CA, AU and US

CONTACT

Carlos Dorronsoro and Susana Marcos

 Intraocular Lens Design

 
This patent has been licenced to AJL Opthalmics, SA (Nov 2007), who also has adquired the exploitation rigths for the associated know-how.
 
CSIC TIC- Analytical design of intraocular lenses

A Spanish research institute has patented a complete methodology to develop Intraocular Lens (IOL) designs and evaluate their performance based on an analytical formulation. The invention provides a systematic method that can lead to more efficient optical designs. The research institute is looking for industrial partners interested in its exploitation.

Specification sheet:

DESCRIPTION

A new approach to the design of intraocular lenses has been developed. This method optimizes the retinal image quality (minimizing simultaneously spherical aberration and defocus) and it can be customized to certain pattern of patients or to individual eyes. This optimization is based on new equations that relate the biometric parameters of the eye with te final retinal image quality, to give a direct stimation of the optimum design parameters of the intraocular lens. It is specially suitable for the design of aspheric intraouclar lenses.

INNOVATIVE ASPECTS

We have developed a new mathematical model to obtain the analitical expressions relating optical quality metrics with the biometric parameter of the eye and the design parameters of the intraocular lens. This allows a direct optimization based on analitical methods. With this method all the solution space can be explored at once and the best global result can be obtained.


COMPETITIVE ADVANTAGES


Current design methods are based on virtual ray tracing, which is computationally costly. Furthermore, it only allows discrete combinations of design parameters and consequently an incomplete screening of the solution space. 

Current designs based on aspherical surfaces present a constant negative spherical aberration to compensate for average spherical aberration of the population. However they do not correct simultaneously refractive lens power and spherical aberration. Our method allows to customize the design parameters according to the biometric parameters of the patient: corneal radius and asphericity, pupil diameter, anterior and posterior chamber depths...

The method can include different complexity levels in the input parameters or output restrictions, and can be used to calculate tolerances of the design, fabrication or implantation of the lens.

KEYWORDS

Medicine, Human Health;Surgery; Optics; Ophtalmology; Intraocular lens; Cataract surgery;

PATENT

Patent applications filed: ES, PCT

CONTACT

Carlos Dorronsoro and Susana Marcos