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Visual Optics and Biophotonics Lab - CSIC - Madrid


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Funding - FEDER
Technology Transfer
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Optical aberrations degrade the images of the outside world projected on the retina. Beyond conventional refractive errors (astigmatism and defocus), optical aberrations arise from the geometry of the ocular surfaces and misaligments. The Spatially Resolved Refractomer (SRR), Laser Ray Tracing aberrometer (LRT) and Hartmann-Shack wavefront sensing have allowed us to measure optical aberrations in normal eyes, eyes with pathologies and following surgery. We have measured aberrations in aging eyes, young eyes as a function of dynamic accommodation, as a function of refractive error (myopes and hyperopes), in keratoconic eyes, investigated their change with myopic and hyperopic LASIK, and cataract surgery (with aspheric and spherical IOLs, accommodating IOLs), intracorneal ring segment implantation. We have also measured optical aber rations in experimental models for myopia (chicken, mouse and marmoset). Measurement of anterior and posterior corneal surface geometry, lens alignment and geometry allows constructing computer eye models customized to the anatomical parameters of each patient. Virtual ray tracing on these model eyes allow calculation of ocular aberrations (with high agreement to measured aberrations) and understanding the contributions of each factor to optical degradation.

 New instruments

  Laser Ray Tracing
  Adaptive Optics
  Simultaneous Vision
  Lens Stretcher
  Ocular microscopy
  Anterior Segment Optical Coherence Tomography
  Ocular aberrations
  Corneal biomechanics

 Selected references

  S. Barbero et al. Journal of the Optical Society of America (2003)
  S.Marcos et al. Vision research (2008)
  E. Gambra et al. Journal of Vision (2009)
  P.Perez et al. IOVS (2013)
  He et al. JOSA 1998
  Marcos et al. Vision Res 1999(a)
  Marcos et al. Vision Res, 1999 (b)
  Applegate et al. JRS 2000
  He et al. Vision Res 2000
  Marcos and Burns. Vision Res 2000
  Moreno-Barriuso et al. IOVS 2001
  McLellan et al. IOVS 2001
  Marcos et al. IOVS 2001
  Marcos et al. Vision Res 2001
  Moreno-Barriuso et al. OVS 2001
  Marcos, JRS 2001
  Barbero et al. JRS 2002
  Barbero et al. JCRS 2002
  McLellan et al. Nature 2002
  Marcos et al. JOSA 2002
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